![]() In cell experiments, it was revealed that Sch B inhibited OS cell proliferation, migration and invasion, and increased OS cell apoptosis. The present study was focused on the effects of Sch B on OS cells (143B, MG63, Saos2 and U2OS) in vitro and in vivo, and also on its possible antitumor mechanisms. Schisandrin B (Sch B) has been previously demonstrated to exhibit antitumor properties. ![]() ![]() Thus, there is an urgent need for the development of safe and effective novel drugs for the treatment of OS. At present, there are several side-effects associated with the OS clinical treatment of OS, with the treatment effects often being unsatisfactory. ![]() Osteosarcoma (OS) is the most common malignant bone tumor worldwide and is associated with a poor prognosis, often being accompanied by lung metastasis at an early stage. ![]()
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January 2023
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